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Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research
Faculty
Medicine
Year:
2021
Type of Publication:
ZU Hosted
Pages:
Authors:
Amira Abdellatif Sallih
Staff Zu Site
Abstract In Staff Site
Journal:
Biomedicine & Pharmacotherapy El SEVIER
Volume:
Keywords :
Host immune response against leishmaniasis , parasite
Abstract:
Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains a major public health problem and is linked to tropical and subtropical regions, with an endemic picture in several regions, including East Africa, the Mediterranean basin and South America. The different causative species display a diversity of clinical presentations; therefore, the immunological data on leishmaniasis are both scarce and controversial for the different forms and infecting species of the parasite. The present review highlights the main immune parameters associated with leishmaniasis that might contribute to a better understanding of the pathogenicity of the parasite and the clinical outcomes of the disease. Our aim was to provide a concise overview of the immunobiology of the disease and the factors that influence it, as this knowledge may be helpful in developing novel chemotherapeutic and vaccine strategies.
Author Related Publications
Amira Abdellatif Sallih, "Assessment of chitosan nanoparticles in improving the efficacy of nitazoxanide on cryptosporidiosis in immunosuppressed and immunocompetent murine models", scopus, 2020
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Amira Abdellatif Sallih, "Hepatosplenic Protective Actions of Spirulina platensis and Matcha Green Tea Against Schistosoma mansoni Infection in Mice via Antioxidative and Anti-inflammatory Mechanisms", frontiers in veterinary science, 2021
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Amira Abdellatif Sallih, "Epidemiological, Morphometric, and Molecular Investigation of Cystic Echinococcosis in Camel and Cattle From Upper Egypt: Current Status and Zoonotic Implications", frontiers in veterinary science, 2021
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Amira Abdellatif Sallih, "Wheat germ and propolis decreased the parasite burden and restored the marked histopathological changes in liver and lung during chronic toxoplasmosis in experimentally infected mice", MDPI, 2022
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Amira Abdellatif Sallih, "Epidemiological and Histopathological Investigation of Sarcocystis spp. in Slaughtered Dromedary Camels (Camelus dromedarius) in Egypt", MDPI, 2020
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Department Related Publications
Marwa Ahmed Mohammed Salameh, "Differentiation & Homing of Bone Marrow-Derived Mesenchymal Stem Cells in the Liver of Schistosoma infected mice.", journal of the egyptian society of parasitology, 2019
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Samira Metwally Mohamed Alii, "PREVALENCE OF INTESTINAL PROTOZOA AMONG PATIENTS WITH INFLAMMATORY BOWEL DISEASE AND IRRITABLE BOWEL SYNDROME.", J.Egypt.Soc.Parasitol.(JESP),, 2019
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Asmaa Mohamed Farouk Fahmy, "Efficacy of olibanum and propolis medicinal extracts versus metronidazole in Giardia lamblia experimentally infected mice", Microbes and Infectious Diseases November 2020; Vol. 1, No.(3), P: 209-220, 2020
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Ashraf Salah Metwaly Abdallah, "تقييم العلاج بدواء السبيراميسين المحمل على جزيئات الكيتوزان على داء المقوسات الحاده والمزمنة Title: Assessment of Spiramycin–loaded chitosan nanoparticles treatment on acute and chronic toxoplasmosis in mice", Journal of parasitic diseases, 2018
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Samyah Alsayed Ibrahiem Atewa, "The impact of anthelminthic therapeutics on serological and tissues apoptotic changes induced by experimental trichinosis", J Parasit Dis, 2018
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