The current work investigated the influences of different light sources on growth performance, carcass characteristics, blood biochemicals, physiological status and health aspects. One hundred and twenty growing California rabbits were assigned into four empirical collections in an experiment of completely randomized design. Rabbits of the first collection were reared under incandescent light bulbs (control), while the second, third and fourth collections were reared under fluorescent, saving light and LED light bulbs, respectively. The results indicated that rabbits reared under incandescent and LED had the heaviest body weight at 16-weeks-old. Rabbits reared under LED recorded the greatest gain during 14–16 weeks of age and 6–16 weeks of age. The lowest feed conversion ratio was observed in rabbits reared under LED lighting, during 14–16 weeks of age, and during the whole period without significant variations. Fat percentage (%) was low in rabbits exposed to fluorescent and LED. Rabbits grown under LED showed the lowest albumin/globulin and the highest glucose concentration. Rabbits kept under LED showed the lowest rectal temperature, mortality and health risks %. Conclusively, LED lighting source might be appropriate for alteration of incandescent and fluorescent light sources in rabbit farms to improve growth performance without compromising rabbit’s carcass and welfare.