End-stage chronic kidney disease is an incurable condition for which dialysis and renal transplantation are the only available treatments. 3D bioprinting strategies in tissue engineering have been proposed to fabricate clinically applicable tissue constructs that can replace damaged or diseased tissues and organs. A tissue-specific bioink is needed to create constructs that provide a biologically competent microenvironment to the encapsulated cells so that they can organize and create the appropriate architecture and functionality of renal tissue. In this study, we hypothesized that kidney ECM materials could provide renalspecific molecules and structural and biomechanical signals to regulate the renal cell behavior and, eventually, tissue maturation and formation. We have developed a photo-crosslinkable kidney ECMderived bioink (KdECMMA) that could provide a kidney-specific microenvironment for renal tissue bioprinting.