Atrial fibrillation and heart failure in cardiology practice: reciprocal impact and combined management from the perspective of atrial fibrillation: results of the Euro Heart …

Faculty Medicine Year: 2009
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Journal of the American College of Cardiology American College of Cardiology Foundation Volume:
Keywords : Atrial fibrillation , heart failure , cardiology practice:    
Abstract:
Objectives: Our aim was to identify shortcomings in the management of patients with both atrial fibrillation (AF) and heart failure (HF). Background: AF and HF often coincide in cardiology practice, and they are known to worsen each other’s prognosis, but little is known about the quality of care of this combination. Methods: In the observational Euro Heart Survey on AF, 5,333 AF patients were enrolled in 182 centers across 35 European Society of Cardiology member countries in 2003 and 2004. A follow-up survey was performed after 1 year. Results: At baseline, 1,816 patients (34%) had HF. Recommended therapy for HF with left ventricular systolic dysfunction (LVSD) with a beta-blocker and either an angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor blocker was prescribed in 40% of HF patients, while 29% received the recommended drug therapy for both LVSD-HF and AF, consisting of the combination of a beta-blocker, either ACEI or angiotensin II receptor blocker, and oral anticoagulation. Rate control was insufficient with 40% of all HF patients with permanent AF having a heart rate ≤80 beats/min. In the total cohort, HF patients had a higher risk for mortality (9.5% vs. 3.3%; p < 0.001), (progression of) HF (24.8% vs. 5.0%; p < 0.001), and AF progression (35% vs. 19%; p < 0.001) during 1-year follow-up. Of all recommended drugs for AF and LVSD-HF, only ACEI prescription was associated with improved survival during 1-year follow-up (odds ratio: 0.51 [95% confidence interval: 0.31 to 0.85]; p = 0.011). Conclusions: The prescription rate of guideline-recommended drug therapy for AF and LVSD-HF is low. Randomized controlled trials targeting this highly prevalent subgroup with AF and HF are warranted. About
   
     
 
       

Author Related Publications

  • Aly Mohamed Abdelrahman Saad, "The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe The Euro Heart Survey on diabetes and the heart", Elsevier, 2004 More
  • Aly Mohamed Abdelrahman Saad, "Treatment and Health Status in Patients with Proven Coronary Artery Disease, but Ineligible for Revascularization. A Report from the Euro Heart Survey on Revascularization", Sage, 2006 More
  • Aly Mohamed Abdelrahman Saad, "Pharmacological treatment and perceived health status during 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization: Results from the Euro Heart Survey on coronary revascularization", Sage, 2006 More
  • Aly Mohamed Abdelrahman Saad, "A 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization. Results from The Euro Heart Survey on Coronary Revascularization", Oxford University Press, 2006 More
  • Aly Mohamed Abdelrahman Saad, "Atrial fibrillation management: a prospective survey in ESC Member Countries", Oxford University Press, 2005 More

Department Related Publications

  • Ahmed Shafea Mahmoud Morsy, "قيمه سمك الطانه والطبقة الوسطي للشريان السباتي والفخذي كعامل غير نافذ للتنبؤ بمرض الشريان التاجي", مجلة القلب المصرية, 2001 More
  • Ahmed Shafea Mahmoud Morsy, "تاثير توسيع الصمام الميترالي بالقسطره البالونية علي الارتجاع الوظيفي للصمام ثلاثي الشرفات وارتفاع ضغط الشريان الرئوي", مجلة جامعة الزقازيق الطبية, 2000 More
  • Tarek Abdelmoniem Abdelaziz, "Human C-reactive protein gene polymorphism andmetabolic syndrome are associated with premature coronary artery disease", Elsevier, 2013 More
  • Tarek Abdelmoniem Abdelaziz, "Synergistic Effect Between Lipoprotein Lipase and Apolipoprotein C3 Genes in Determining the Severity of Coronary Artery Disease", Springer, 2013 More
  • Eslam Alsayed Mohamed Mohamed Shehata, "Mitral annulus time intervals for assessment of left ventricular systolic function in ischemic cardiomyopathy", European Journal of Heart Failure Supplements (2012) 11, S128–S177, 2012 More
Tweet