The recent research aimed to explore the effects of age, job, and number of experience years on teaching staff and their assistants’ psychological empowerment, also to check the relationship between psychological empowerment and transformational leadership and their dimensions, moreover to verify the relationship between transformational leadership and work engagement and their dimensions, in addition to identifying the effect of psychological empowerment mediation on the relationship between transformational leadership and work engagement. Number of final sample was (258) teaching staff members and their assistants in faculties of Education, Specific Education, Physical Education for Boys, and Physical Education for Girls, Zagazig University, were chosen randomly, and research tools were administered (psychological empowerment measure, transformational leadership measure, and work engagement measure); all are translated by the researchers. Statistical methods were One-Way Between-Subjects MANOVA, R Squared, Pearson Correlation, and a structural equation model. The most important results were: there are statistically significant differences according to age in favor of the age category (more than (60) years), there are statistically significant differences according to job in favor of (Professor) job, also there are statistically significant differences according to number of experience years in favor of (more than (40) years of experience), moreover there is a statistically significant relationship between psychological empowerment and transformational leadership and their dimensions, also there is a statistically significant relationship between transformational leadership and work engagement and their dimensions, in addition to that both psychological empowerment and transformational leadership can predict about 46% of variance in work engagement.