The thermally driven adsorption desalination cycle has been considered a promising solution to mitigate the gap between freshwater needs and demands. Silica gel and zeolite are commonly used in the cycle however, they have low capacity. So, metal–organic framework adsorbents have been proposed as a replacement for silica gel and zeolite. Performance of the adsorption desalination cycle using metal–organic framework materials has been extensively investigated numerically with limited available experimental measurements in the open literature. In this work, a lab-scale adsorption desalination cycle using heat recovery was built using a metal organic framework (CPO-27(Ni)) as an adsorbent. Effect of the cycle time, switching time, condenser type, and cooling water temperature is assessed from the viewpoint of the cycle’s specific daily water production and gained output ratio. This investigation aims to …