The Role of Osteopontin in the Pathogenesis and Complication of Type 1 Diabetes Mellitus in Children

Faculty Medicine Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Mohamed Ahmed Talaat Kamal
Journal: Journal of Clinical Research in Pediatric Endocrinology Turkish Pediatric Endocrinology and Diabetes Society Volume: 1308-5727
Keywords : , Role , Osteopontin , , Pathogenesis , Complication , Type , Diabetes    
Abstract:
Aim: To investigate the levels of serum osteopontin in pediatric patients with T1DM and to explore if these levels have a role in the prediction of diabetes complications. Conclusion: T1DM Patients had higher osteopontin levels than controls . -T1DM patients with microalbuminuria had serum osteopontin levels higher than in patients with normal albumin excretion rate and in the control group. -T1DM patients with retinal disease had higher serum osteopontin levels than those without . -Increased osteopontin levels are independently associated with T1DM in pediatric patients and supports the hypothesis that osteopontin may have a role in the prediction of microvascular diabetes complications.
    
     
 
       

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