The effect of sesame intake on adult albinorat testis during sildenafil long-termadministration

Faculty Science Year: 2021
Type of Publication: ZU Hosted Pages:
Authors:
Taher Mohammed Ahmed AbuAlnasr
Journal: MIRT Journal MIRT JOURNAL Volume:
Keywords : , effect , sesame intake , adult albinorat testis    
Abstract:
Background:Sildenafil (Viagra) is widely used for the treatment of erectile dysfunction under various etiologies.Unfortunately, chronic administration of sildenafil negatively affects fertility. The aim of the present study is toinvestigate the improvement role of sesame on the testis alterations caused by long-term administration ofsildenafil on albino rats.Results:Light microscopically observations showed that overdoses of sildenafil had provoked tubular andinterstitial histological alterations. Tubular degeneration and abnormality in the germinal epithelium of theseminiferous tubules included spermatocyte degeneration and arrest of spermatogenesis. Sperm count and motilitywere negatively affected by sildenafil. These alterations were improved by sesame feeding.Conclusion:Sesame intake improve the side effects of prolonged treatment with sildenafil significantly. Theseresults demonstrate the pivotal role of sesame that may improve male infertility.
    
     
 
       

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  • Taher Mohammed Ahmed AbuAlnasr, "Observations on the food and feeding habits of whipfin mojarra, Gerres filamentosus (Cuvier, 1829) in the Hurghada Red Sea", Zagazig University International conference 10 th, 2015 More

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