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Association between interleukin -4 gene polymorphism with the risk and disease activity of Egyptian patients with systemic lupus erythematosus
Faculty
Medicine
Year:
2020
Type of Publication:
ZU Hosted
Pages:
Authors:
Nevin fouad ibrahim salama
Staff Zu Site
Abstract In Staff Site
Journal:
Zagazig University Medical Journal Zagazig University
Volume:
Keywords :
Association between interleukin , gene polymorphism with
Abstract:
Background: Cytokines are a heterogeneous group of molecules organizing different processes of the immune response. Interleukin -4 (IL-4) modulates various immune functions. It plays a vital role in the development of systemic lupus erythematosus (SLE). We aimed to explore the correlation of IL-4 C-589T (rs2243250) gene polymorphism with SLE and its association with disease activity. Method: This study included 100 SLE patients and 90 healthy controls. Disease activity was evaluated by Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). Samples from all participants were analyzed for IL-4 589 genotyping by restriction fragment length polymorphism (RFLP) and serum IL-4 level by enzyme linked immunosorbent assay (ELISA).
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Nevin fouad ibrahim salama, "Prevalence of occult hepatitis C virus infection in patients who achieved sustained virologic response to direct-acting antiviral agents", Le infezioni in medicina, 2018
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Nevin fouad ibrahim salama, "Mannose-Binding Lectin Serum Level and Gene Polymorphism in Systemic Lupus Erythematosus Egyptian Patients", The Egyptian Journal of immunology, 2020
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Nevin fouad ibrahim salama, "Association of Receptor Activator of Nuclear Factor-κB Ligand (RANKL) and Osteoprotegerin with Secondary Hypogonadism in Egyptian Females with Beta-Thalassemia Major", Ain shams university, 2021
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Nevin fouad ibrahim salama, "Association of Circulatory Long Non-Coding RNA AFAP1-AS1 with Risk and progression of Pr Hepatocellular Carcinoma in Egyptian Patients with Chronic Hepatitis C Virus Infection", Ain shams university, 2021
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Nevin fouad ibrahim salama, "Serum biomarkers of hepatocellular carcinoma in patients with liver cirrhosis: a narrative review", scientific society of kafr el-sheikh doctorss, 2021
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Department Related Publications
Ahmed Adel Hassan Muhamad, "دراسة سريرية مرضية لالتهاب الكبد الهلالى المتكاثر عند الاطفال", لايوجد, 1900
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Ahmed Adel Hassan Muhamad, "ثبات وظائف الكلى المزروعة فى المستقبلون للكلى ويعالجون بعقار السانداميسون متابعة طويلة المدى", لايوجد, 1900
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Ahmed Adel Hassan Muhamad, "دراسة الاجسام المضادة لمضادات الكارديولابيبين ومتلازمة الكارديولابيبين فى مرضى الروماتويد المفصلى", لايوجد, 1900
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Ahmed Adel Hassan Muhamad, "الاجسام المضادة السامة للخلايا الليمفاوية للزوج فى حالات ارتفاع ضغط الدم المصاحب للحمل", لايوجد, 1900
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Ahmed Adel Hassan Muhamad, "تأثير من انظمة التثبيط المناعى على انتاج مادة عوامل النمو المحولtof-B1 فى متلقى زرع الكلى", لايوجد, 1900
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