Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Trans Fatty Acid Intake Modulates the Expression of Uncoupling Proteins 2 and 3 (UCP2 & UCP3) mRNA in Children.
Faculty
Medicine
Year:
2021
Type of Publication:
ZU Hosted
Pages:
Authors:
Walaa Mohamed Ibrahim Sarhan
Staff Zu Site
Abstract In Staff Site
Journal:
Current Research in Nutrition and Food Science Enviro Research Publishers
Volume:
Keywords :
Trans Fatty Acid Intake Modulates , Expression
Abstract:
ncreased consumption of Trans Fats is associated with increased risk of Coronary Heart Disease. Uncoupling proteins (UCPs) are mitochondrial proteins that disperse the inter-membrane electrochemical potential as heat. We aimed to detect the relation of high Trans-fat intake in diet on the expression of UCP2&3 m-RNA in children. A specific questionnaire to parents of sixty-eight children (4-15 years) was conducted. Accordingly, the subjects were sub-grouped into; High Trans-fat consuming group (37 subjects) and a Medium Trans-fat consuming one (31 subjects). Samples collected from Peripheral blood to analyze UCP2&3 mRNA expression by Real Time Polymerase Chain Reaction (RT-PCR). Levels of UCP2 expression was reduced in children consuming High Trans-fat (2.5 ±0.7) in comparison with Medium Trans-fat consuming ones (1.5± 0.2) with (p<0.001). However, not much significance was showed in UCP3 expression with values (2.1±0.5) in the High consuming group and (1.9±0.2) in Medium consuming group with (p=0.08). In Delta relationship the diet-induced changes in UCP2 (r=0.66, P=0.002) and UCP3 (r=0.61, P=0.06) mRNA expression was negatively correlated with percentage of Trans-fat in diet.
Author Related Publications
Walaa Mohamed Ibrahim Sarhan, "EVALUATION OF ETHOSOMAL EPIGALLOCATECHIN-3-GALLATE GEL FORMULATIONS AS AN ANTIOXIDANT AND THERMOGENIC AGENT", INNOVARE ACADEMIC SCIENCE, 2020
More
Walaa Mohamed Ibrahim Sarhan, "dapk-1 gene methylation pattern in some leukemic patients attending zagazig university hospitals ... is it a clue ?", international journal of research in medical science, 2016
More
Walaa Mohamed Ibrahim Sarhan, "Urinary exosomal microRNA-96-5p and microRNA-183-5p expression as potential biomarkers of bladder cancer", springer, 2021
More
Walaa Mohamed Ibrahim Sarhan, "Uncoupling Protein 2 Expression Modulates Obesity in Chronic Kidney Disease Patients", BMB, 2021
More
Walaa Mohamed Ibrahim Sarhan, "Assessment of INPP4B Expression Level in Acute Myeloid Leukemia Patients and Its Prognostic Significance. An Egyptian Study", الدوريات المصريه, 2021
More
Department Related Publications
Amal Alsayed Sehata Morssi, "20. معدلات تدفق الدم بالنسيج الضام للمبيض باستخدام الدوبلر ذو الطاقة ثلاثى الابعاد وعامل النمو للخلايا المبطنة للاوعية الدموية في متلازمة تكيس المبيض عقب تثقيب المبيض بمنظار البطن ", لايوجد, 1900
More
Diab Ahmed Radwan, "ارتباط عامل نمو العصب و الانترلوكين -4 و-5 في حدوث الربو الشعبى و دورهم فى تنشيط خلايا الاوزينوفيل", لايوجد, 1900
More
Diab Ahmed Radwan, "تاثير ثيوسلفات الصوديوم و الميلاتونين علي الاثار السميه لعقار السيزبلاتين على الاذن و الكلى و خطوره الاكسده فى الجرزان البيضاء البالغه", لايوجد, 1900
More
Sami Hassan Ibrahim, "دور فيروس الالتهاب الكبدي س في حدوث مرض الرثيان المفصلي.", لايوجد, 1900
More
Sami Hassan Ibrahim, "اهميه قياس عامل نمو خلايا بطانه الاوعيه الدمويه في مصل دم مرضي سرطان الكبد", لايوجد, 1900
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف