Value of antifungal susceptibility testing in recurrent vulvovaginal Candidiasis by Non -Albicans Candida

Faculty Medicine Year: 2021
Type of Publication: ZU Hosted Pages: 161-167
Authors:
Journal: Egyptian Journal of medical microbiology Cairo university Volume:
Keywords : Value , antifungal susceptibility testing , recurrent vulvovaginal    
Abstract:
Background: Vulvovaginal candidiasis (VVC) is regarded as a prevalent vaginal infection and mainly results from Candida albicans. Nevertheless, there has recently been a prominent shift in candidiasis etiology regarding non-albicans Candida (NAC) species with achieving importance. For women with more than three episodes annually are described as recurrent vulvovaginal candidiasis (RVVC). Objectives: To isolate, speciate, and determine the value of antifungal sensitivity pattern of candida species isolated from patients developed (RVVC). Methodology: High vaginal swabs (HVS) were taken from patients with RVVC and cultured on ordinary mycological media. Any significant candida growth was identified and speciated by VITEK 2 system. Their antifungal sensitivity was done by disc diffusion approach governed by CLSI guidelines. Results: A total of 110 Candida species from 250 high vaginal swabs were isolated. Among all candida species isolated from patients with RVCC, C.albicanis accounts for 44% while NAC accounts for 56% with C.glabrata most common species isolated. Voriconazole, amphotericin B, and nystatin showed high sensitivity rates (92 %, 89%, and 84% respectively) on all candida species (C.albicans and NAC) isolated from patients with RVVC. Conclusion: In RVCC there is increase in NAC (56%) with C.glabrata most common species isolated. Voriconazole, Nystatin, and amphotericin B have the best antifungal activity against all spp
   
     
 
       

Author Related Publications

    Department Related Publications

    • Ashwak Mohamed Foad Abotaleb, " اختبار حساسية المعزولات الاكلينيكيةلميكروب المتفطرة التدرنية بواسطة ثلاثه طرق مختلفة", لايوجد, 1900 More
    • Hanan Mohamed Elsayed Ibrahiem, "Serum YKL-40 as a Marker of Articular Manifestations In Inflammatory Bowel Disease", لايوجد, 1900 More
    • Hanan Mohamed Elsayed Ibrahiem, "HLA-DRB genotyping in patients with systemic lupus erythematosus:correlations with different clinically defined subsets. 3 /5 /2000 Zagazig University Medical J ", لايوجد, 1900 More
    • Refaat Abdelsamiea Sadek, ")Comparative studies on the rapid laboratory methods for the diagnosis of bacterial meningitis. ", لايوجد, 1900 More
    • Refaat Abdelsamiea Sadek, ") Effect of normal human blood serum on the growth of Dermatophytes ", لايوجد, 1900 More
    Tweet