Value of antifungal susceptibility testing in recurrent vulvovaginal Candidiasis by Non -Albicans Candida

Faculty Medicine Year: 2021
Type of Publication: ZU Hosted Pages: 7
Authors:
Journal: Egyptian Journal of Medical Microbiology Egyptian Journal of Medical Microbiology Volume:
Keywords : Value , antifungal susceptibility testing , recurrent vulvovaginal    
Abstract:
Background: Vulvovaginal candidiasis (VVC) is regarded as a prevalent vaginal infection and mainly results from Candida albicans. Nevertheless, there has recently been a prominent shift in candidiasis etiology regarding non-albicans Candida (NAC) species with achieving importance. For women with more than three episodes annually are described as recurrent vulvovaginal candidiasis (RVVC). Objectives: To isolate, speciate, and determine the value of antifungal sensitivity pattern of candida species isolated from patients developed (RVVC). Methodology: High vaginal swabs (HVS) were taken from patients with RVVC and cultured on ordinary mycological media. Any significant candida growth was identified and speciated by VITEK 2 system. Their antifungal sensitivity was done by disc diffusion approach governed by CLSI guidelines. Results: A total of 110 Candida species from 250 high vaginal swabs were isolated. Among all candida species isolated from patients with RVCC, C.albicanis accounts for 44% while NAC accounts for 56% with C.glabrata most common species isolated. Voriconazole, amphotericin B, and nystatin showed high sensitivity rates (92 %, 89%, and 84% respectively) on all candida species (C.albicans and NAC) isolated from patients with RVVC. Conclusion: In RVCC there is increase in NAC (56%) with C.glabrata most common species isolated. Voriconazole, Nystatin, and amphotericin B have the best antifungal activity against all spp
   
     
 
       

Author Related Publications

  • Ghada Abdelmoneiem Mokhtar Ahmed, "CMV, B and C hepatitis among multitransfused hereditary hemolytic Anemia children: an updated Egyptian experience", italian journal of pediatric, 2021 More
  • Ghada Abdelmoneiem Mokhtar Ahmed, "Genetic polymorphism of vitamin D receptors and plasminogen activator inhibitor-1 and osteonecrosis risk in childhood acute lymphoblastic leukemia", molecular genetic and genomic medicine, 2021 More
  • Ghada Abdelmoneiem Mokhtar Ahmed, "Vitamin D deficiency and vitamin D receptor gene polymorphisms as a risk factor for severe early-onset neonatal sepsis", Alexandria Journal of Pediatrics 2018,, 2018 More
  • Ghada Abdelmoneiem Mokhtar Ahmed, "Comparison between Specific Immunoglobulin E and Skin Prick Test for Diagnosis of Allergic Patients", Egyptian Journal of Medical Microbiology, 2020 More
  • Ghada Abdelmoneiem Mokhtar Ahmed, "Fungal profile of otomycosis in a sample of Egyptian patients in Zagazig university hospitals: A prospective study", Microbes and Infectious Diseases, 2021 More

Department Related Publications

  • Ashwak Mohamed Foad Abotaleb, "تشخيص اصابة عنق الرحم بالكلاميديا تراكوماتيس بواسطه التفاعل المتسلسل لانزيم البلمره", لايوجد, 1900 More
  • Ashwak Mohamed Foad Abotaleb, "اختبار فيروس الالتهاب الكبدي س وتحديد النوع الجينى في المتبرعين بالدم", لايوجد, 1900 More
  • Amal Hassan Mahmoud Atta , "diagnosis of chlamydia trachomatis endo-cervical infection by polymerase chain reaction assay", لايوجد, 1900 More
  • Hanan Mohamed Elsayed Ibrahiem, "Comparison of PCR Assay to Culture for Detection of Vancomycin Resistant Enterococci Colonizing the Intestinal Tract of Hospitalized patients", لايوجد, 1900 More
  • Hanan Mohamed Elsayed Ibrahiem, "Persistance of protective antibody titer following 3-doses regimen hepatitis b vaccination; for how long? 1 /1 /1998 Zagazig University Medical J ", لايوجد, 1900 More
Tweet