Introduction: Enhanced RMGIs were presented to the market in 2013 by Pulpdent Corporation named ACTIVA BioACTIVE restorative material (ACTIVA). Bioactiva is a bioactive composite with ionic resin matrix aiming to enhance both resilience and physical properties. The aim of this study: To perform a comparison between ACTIVA BioACTIVE restorative, Nano-filled dental composite and RMGIC for compressive and flexural strength. Materials and methods: A total of 60 specimens were made of (ACTIVA Bioactive-, Filtek Z350XT and Ketac Nano-100 RMGI), thirty cylindrical shaped specimens were prepared for compressive strength testing using A split Teflon mold (8 mm height, 4 mm diameter) and other 30 specimens were prepared for flexural strength testing using A split teflon mold with (2 x 2 x 25 mm) measurements. All specimens were kept in distilled water for 24 h, then they were tested by universal testing machine. ANOVA, One way Analysis of variance, and Tukey post hoc test were performed to determine differences between the groups Results: The Filtek Z350XT recorded the highest values for compressive and flexural strength, while the lowest values were for Ketac Nano-100. There was no statistically significant difference between compressive strength values of Filtek Z350XT and ACTIVA. While there was a significant difference among flexural strength values for all the materials. Conclusion: ACTIVA demonstrates mechanical properties comparable to dental composite and superior to traditional RMGIC.