Abstract: Introduction: Through-out the significant developments occurred in dentistry, it was very important to preserve the vitality of the dental pulp as possible to ensure a long life to tooth in oral cavity. The dental pulp has a high capacity to repair itself after traumatic exposure, either in human or in animals. The use of appropriate material to cover the exposed pulp increases rate of success and contributes to maintain the vitality of the dental pulp. Aim of the work: The aim of the current study was to evaluate the impact of a new silicate-based capping material on healing potential of traumatically exposed healthy dog’s dental pulp Materials and Methods: Two pulp capping materials were evaluated in this study; Mineral trioxide aggregate (MTA), and Five mineral oxides (5MO). Glass ionomer as overlying restorative material. Six adult healthy dogs with intact permanent dentition were selected for the study. A total of sixteen anterior teeth were used in each dog. Both pulp capping materials were used in the same dog. Class V cavities were prepared on the teeth. After pulp exposure, the pulp capping materials were applied directly to the exposed pulp. All cavities were sealed with glass ionomer restorative material. The used six dogs were divided into two groups; three dogs each, according to the capping periods to 7 days and 90 days. Results: Histological evaluation after 7 days of direct pulp capping, both group have severe and moderate inflammation with no dentin bridge formation. After 90 days of direct pulp capping, a calcified bridge was formed directly underneath the capping material at the injury site in both the MTA and 5MO groups; both groups showed no signs of inflammation. Conclusions: There is no significance difference between MTA and 5MO when used as direct pulp capping material