Background: No agreement between the orthopedic surgeons regarding the best treatment for the diaphyseal tibial fracture in children. Hypothesis: The flexible intramedullary nailing technique is a valuable procedure with the lower reported incidence of complications for pediatric patients suffering from diaphyseal tibial fractures in the age group that ranges from 6 to 12 years old. Materials and Methods: This study was performed prospectively on 16 pediatric patients who underwent flexible intramedullary nailing for the management of the diaphyseal tibial fractures. Results: The final results in 12 patients (75%) were excellent and satisfactory in four patients (25%). The average time of clinical union was 6.75 ± 1.12 weeks, while the average time of radiological union was 9.31 ± 0.79. Discussion: The results of the present study were according to other authors raising our hypothesis that flexible intramedullary nailing procedure has many advantages for children suffering from diaphyseal tibial fractures for the age group between 6 and 12 years old when compared to other methods of fixation. Conclusions: We prefer the flexible intramedullary nailing procedure as the first choice to treat the unstable diaphyseal tibial fractures in the pediatric age group between 6 and 12 years old, because it is, less invasive, low chance of infection, refracture, and implant failure