In this study, a finite element analysis was performed to investigate and evaluate the pavement responses (Vertical Displacement and Total Stresses) for asphalt mixtures modified using different types of additives. The PLAXIS 2D Package software was used to simulate and model the proposed pavement structure. The proposed pavement structure consists of 10 cm asphalt wearing courses, 30 cm aggregate base course rested on subgrade material with CBR 15%. The infinity subgrade depth was represented in the model by depth 2.00 m. The asphalt layer was represented in the finite element model by five mixtures that modified by using five types of additives. The additives included Nano Silica, Silica Fume, Lime, Rubber, and Polymer. An experimental program was conducted to specify the Modulus of resilience and Poison's Ratio for each of the modified mixtures as well as the control mix. The finite elements analysis results of the tested mixtures indicated that the asphalt mixture modified using silica fume is the most resisting deformation and stresses under different traffic loads.