Foodborne illness as a result of microbiological contamination (parasitic infestations and bacterial contamination) of slaughtered carcasses and edible offal have a significant impact on human health and causes economic losses particularly in developing countries. A total of 4723 of cattle slaughtered at Sharkia governorate abattoirs, Egypt from January 2018 to December 2018 were investigated for the presence of Cysticercus bovis. Furthermore, a total of 80 samples of edible kidney and liver (40 of each) have been collected randomly from different animal species (Cattle, buffalo, camel and sheep, 10 of each) to detect S. aureus, E. coli and Salmonella spp. The results revealed that the prevalence of C. bovis was 0.78% and the most infected site was heart (86.49%) followed by masster muscles (13.51%). In addition, the present results showed that the examined edible offal were contaminated with S. aureus and E. coli while, the examined samples were free from Salmonella spp.