Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Clinical Outcomes of Upper Gastrointestinal Bleeding in Egyptian Patients with Decompensated Liver Cirrhosis, Does the Bleeding Source Matter?
Faculty
Medicine
Year:
2020
Type of Publication:
ZU Hosted
Pages:
Authors:
Mohammed Ahmed Ali Bassiouni
Staff Zu Site
Abstract In Staff Site
Journal:
Egyptian journal of hospital medicine Ain Shams University
Volume:
Keywords :
Clinical Outcomes , Upper Gastrointestinal Bleeding , Egyptian
Abstract:
Background: Upper gastrointestinal bleeding (UGIB) is a prevalent emergency and mortality cause in cirrhotic patients. It prolongs the hospital length of stay (LOS) and increases hospital readmission. Objectives: We investigated the clinical outcomes of acute variceal bleeding (AVB) and non-variceal bleeding (NVB) in patients with decompensated cirrhosis and the possible risk factors for prolonged hospital LOS. Patients and Methods: All patients with decompensated liver cirrhosis and UGIB (AVB & NVB) hospitalized from August 2018 to March 2019 were enrolled in this study. We assessed mortality rate, the hospital LOS and hospital readmission rate along with the probable risk factors associated with prolonged hospital LOS. Results: Our study included 582 patients with decompensated liver cirrhosis, 367 patients had AVB and 215 patients had NVB. There was no significant difference in mortality rate between both groups (11.4% vs. 9.3%, P= 0.43). The hospital LOS in AVB patients was longer than that in NVB group (5.8 ± 2.2 vs. 4.3 ± 1.8, p=0.001). Rate of hospital re-admission within 30 days was significantly higher in the AVB group (27%) compared to NVB group (18%). Inhospital re-bleeding and the need for repeated endoscopy were also higher in AVB patients (20%) than in NVB patients (12%). Risk factors for prolonged hospital LOS were development of hepatic encephalopathy, spontaneous bacterial peritonitis (SBP), in-hospital re-bleeding, Child C score and higher Model for end-stage liver disease (MELD) score. Conclusion: Patients with decompensated cirrhosis and AVB have longer hospital LOS and re-hospitalization rate than those with NVB with no significant difference in mortality rate between both groups
Author Related Publications
Mohammed Ahmed Ali Bassiouni, "Sofosbuvir and daclatasvir plus ribavirin treatment improve liver function parameters and clinical outcomes in Egyptian chronic hepatitis C patients", Wolters Kluwer Health, Inc., 2017
More
Mohammed Ahmed Ali Bassiouni, "Lipocalin-2: A novel diagnostic marker for hepatocellular carcinoma", IOS press, 2020
More
Mohammed Ahmed Ali Bassiouni, "Management of HCV‑related decompensated cirrhosis with direct‑acting antiviral agents: who should be treated?", Springer, 2019
More
Mohammed Ahmed Ali Bassiouni, "Prevalence and Risk Factors of Minimal Hepatic Encephalopathy in Patients with Compensated Liver Cirrhosis", Ain Shams University, 2020
More
Mohammed Ahmed Ali Bassiouni, "The significance of bariatric surgery in Egyptian patients with metabolic syndrome: a multicenter study", Wolter Kluwer - MedKnow, 2020
More
Department Related Publications
Ayman Abdalrahman Mohamed Nasrllah, "Thyroid Dysfunction and Inflammatory Biomarkers in COPD:Relation to Severity and Exacerbation", Cairo,Egypt, 2013
More
Emad Fawzy Hamed Mahmoud, "ANNEXIN A2 VERSUS AFP AS AN EFFICIENT DIAGNOSTIC SERUM MARKER FOR HEPATOCELLULAR CARCINOMA", المجله المصريه الافريقيه للامراض المتوطنه, 2013
More
Emad Fawzy Hamed Mahmoud, "PARAOXONASE 1 Gene Polymorphism Relationship with Type 2 Diabetes Mellitus", life science journal, 2012
More
Ayman Abdalrahman Mohamed Nasrllah, "Microalbuminurea Screening and Risk factors in adolescents with type 1 Diabetes Mellitus In Zagazig University Hospital n", London, 2012
More
Ayman Abdalrahman Mohamed Nasrllah, "Predicting Insulin Resistance Using Triglyceride to High Density Lipoprotein Ratio In Egyptian Adults", Zagazig University,Medical College, 2013
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف