Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
The effect of cigarette smoking on lung cancer evolution
Faculty
Science
Year:
2019
Type of Publication:
ZU Hosted
Pages:
Authors:
Ahmed Nagah Saeed Majid
Staff Zu Site
Abstract In Staff Site
Journal:
Mathematical Biosciences and Engineering Arizona State University
Volume:
Keywords :
, effect , cigarette smoking , lung cancer evolution
Abstract:
The aim of this paper is to elucidate the risk of lung carcinogenesis from cigarette smoking among current and former smokers. To achieve this goal, we have set up a stochastic three-stage model to fit the data of Surveillance, Epidemiology, and End Results (SEER) program besides the data set of smoking derived from the Nurses’ Health Study cohort of females (NHS) and the Health Professionals Follow up Study cohort of men (HPFS). The calculations are performed by considering both mutation and clonal expansion rates as parameters in each compartment. For current smokers, our findings show that cigarette smoking has more significant impact on the mutation rates of cells than the clonal expansion rates of premalignant cells among men and women. In particular, for male patients, cigarette smoking affects the mutation in normal cells and the transformation from premalignant cells to malignant ones in the optimal model. In addition, cigarette smoking induces only the initial mutation rates in normal cells among American women. For current and former smokers, cigarette smoking stimulates only the clonal expansion rate of the first premalignant cells in both sexes. However, we find that the impact of cigarette smoking is minimal in former smokers who have stopped smoking for over ten years among men and women in US.
Author Related Publications
Ahmed Nagah Saeed Majid, "Proton and antiproton impact excitation of H(2s) atom", Canadian Journal of Physics, 2015
More
Ahmed Nagah Saeed Majid, "Optimal Control for Systems Described by Semi-linear Parabolic Equations", World Scientific and Engineering Academy and Society, 2018
More
Ahmed Nagah Saeed Majid, "Mathematical modeling of female breast cancer in Japan", World Scientific Publishing Co. Pte Ltd, 2020
More
Ahmed Nagah Saeed Majid, "Different Mechanisms of Cigarette Smoking‑Induced Lung Cancer", Springer Netherlands, 2020
More
Ahmed Nagah Saeed Majid, "Mutation Mechanisms of Breast Cancer among the Female Population in China", Bentham Science Publishers B.V., 2020
More
Department Related Publications
Rodyna Ahmed Mahmoud, "Pre-Open Sets with Ideal", Scientific Research Platform (SRP), 2013
More
Rodyna Ahmed Mahmoud, "ON BCL-ALGEBRA", Council for Innovative Research, 2013
More
Yasser AbdelAziz Amer Tolba, "The improved (G’/G) - expansion method for constructing exact traveling wave solutions for a nonlinear PDE of nanobiosciences", USA, 2013
More
Alaa Hassan Attia Hassan, "A Unified Representation of Some Starlike and Convex Harmonic Functions with Negative Coefficients", AGH University of Science and Technology Press, Krakow 2013, Poland, 2013
More
Alaa Hassan Attia Hassan, "Generalizations of Hadamard Procuct of Certain Meromorphic Multivalent Functions with Positive Coefficients", Istanbul Universitesi, Turkey, 2013
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف