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The enhancing effects of Biobran/MGN‑3, an arabinoxylan rice bran, on healthy old adults’ health‑related quality of life: a randomized, double‑blind, placebo‑controlled clinical trial
Faculty
Medicine
Year:
2020
Type of Publication:
ZU Hosted
Pages:
11
Authors:
Ahmed Farouk Elsayed Elsayed Ahmmed
Staff Zu Site
Abstract In Staff Site
Journal:
QUALITY OF LIFE RESEARCH SPRINGER
Volume:
29
Keywords :
, enhancing effects , Biobran/MGN‑3, , arabinoxylan rice bran, on
Abstract:
Purpose The world’s older population is growing rapidly and the need to find measures to combat age-associated decline of physical, mental, and cognitive functions and improve their health-related quality of life (HRQOL) is escalating. Biobran/ MGN-3, an arabinoxylan rice bran, has been previously reported to improve the quality of life in cancer patients. The objective of the current study was to examine the effect of a low dose of Biobran/MGN-3 supplementation on the HRQOL in a healthy older adult population. Methods Sixty apparently healthy subjects, 40 males and 20 females, over 56 years old were recruited and blindly randomized into two group receiving either placebo or Biobran/MGN-3 (250 mg/day for 3 months). Participants did not take any vitamins or medications during the study and their health was closely monitored. HRQOL was assessed at the initiation and termination of the study using the previously validated Arabic version of SF-12v2 questionnaire. Results For all measured HRQOL domains, there was no statistically significant difference in baseline scores between the two groups. Compared to baseline values and placebo-treated subjects, Biobran/MGN-3 supplementation significantly enhanced the levels of physical and mental component summary scores as well as role-physical, bodily pain, vitality, and social functioning subdomain scores. Conclusion These results show that Biobran/MGN-3 is a promising psychoneuroimmune modulatory agent that could improve the HRQOL in healthy old adults. Keywords Biobran/MGN-3 · Older adults · Health-related quality of life · Social behavior · Cognitive activity
Author Related Publications
Ahmed Farouk Elsayed Elsayed Ahmmed, "Dietary Supplementation with Biobran/MGN-3 Increases Innate Resistance and Reduces the Incidence of Influenza-like Illnesses in Elderly Subjects: A Randomized, Double-Blind, Placebo-Controlled Pilot Clinical Trial", MDPI, 2021
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Ahmed Farouk Elsayed Elsayed Ahmmed, "Infarction Size, Interleukin-6, and Their Interaction Are Predictors of Short-Term Stroke Outcome in Young Egyptian Adults", Journal of Stroke and Cerebrovascular Diseases, 2016
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Ahmed Farouk Elsayed Elsayed Ahmmed, "Association of Plasma Epidermal Growth Factor with Cognitive Function in Parkinson Disease Patients", Egypt J Neurol Psychiat Neurosurg, 2016
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Ahmed Farouk Elsayed Elsayed Ahmmed, "Statins attenuate hyperalgesia and inflammation in experimentally induced acute and neuropathic pain in rats", Ain-Shams Journal of Anaesthesiology, 2016
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Ahmed Farouk Elsayed Elsayed Ahmmed, "The Effect of Probiotics on Interleukin- 8 and Intestinal Flora in Irritable Bowel Syndrome in Hospital of Zagazig University", Zagazig Nursing Journal, 2016
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