Chemical and biological studies on charge-transfer complexes of cimetidine with various electron acceptors

Faculty Specific Education Year: 2019
Type of Publication: ZU Hosted Pages: 1-11
Authors:
Akmal Shawky Gaballa
Journal: Journal of Molecular Structure Elsevier B.V. Volume: 127256
Keywords : Chemical , biological studies , charge-transfer complexes of cimetidine    
Abstract:
Interaction of Cimetidine drug (CIM) with p-acceptors as Tetracyanoethylene (TCNE) and 7,70,8,80-Tetracyanoquinodimethane (TCNQ), chloranilic acid (H2CA) picric acid (HPA) resulted through the initial formation of ionic intermediate to charge transfer (CT) complex which detected by spectroscopic studies. The molar ratio was found to be 1:1 between cimetidine drug and different acceptor. The formed CT complexes have been characterized using various techniques such as the elemental analyses, UVeVis., IR, and 1H NMR spectra, and thermal analyses (TG, DTG). The antibacterial activity of the complexes were estimated.
    
     
 
       

Author Related Publications

  • Akmal Shawky Gaballa, "Preparation, spectroscopic characterizations and biological studies of a new charge transfer complex formed between fluconazole drug with various acceptors", Elsevier B.V., 2021 More
  • Akmal Shawky Gaballa, "Surface improvement of cotton/polyester blend textile using DC air glow discharge plasma", IOP publishing, 2021 More
  • Akmal Shawky Gaballa, "Synthesis, characterization and acaricidal activity of the organophosphorous chloropyrifosmetal complexes", Austoria, 2021 More
  • Akmal Shawky Gaballa, "Syntheses and identification of cefotaxime-non-transition metal complexes", JK Welfare & Pharmascope Foundation, 2021 More
  • Akmal Shawky Gaballa, "Platinum Complexes with Bioligands: From [H13O6]+ to Carbohydrate Complexes of Platinum(IV)", Prog. in Coord. and Bioinorg. Chem., Slovak Tech. Univ. Press, Bratislava, 2003 More

Department Related Publications

  • Maher Abdul Rahman Shams al-Din Safty, "preparation and characterisation of some polyester- urethanes and polyester - urethane - ureas based on bis - 1.3(carboxy methoxy) benzene", لايوجد, 1900 More
  • Maher Abdul Rahman Shams al-Din Safty, "thermal stability of sulphur compounds of land balayeem drude oil", لايوجد, 1900 More
  • Walaa Helmy Fahmy Sheweny, "Spectroscopic studies, thermal analyses and biological evaluation of new V(IV), Zr(IV) and U(VI) moxifloxacin complexes", elesiever, 2011 More
  • Hamdy Aldedamony , "preparation of β-dicalcium silicate (β-C2S) and calcium sulfoaluminate (C3A3CS) phases using non-traditional nano-materials.", Construction and building materials, 2014 More
  • Hamdy Aldedamony , "Effect of delaying addition time of SMF superplastioced on hydration characteristics of blended cement pastes", Ceramics- silikaty, 2012 More
Tweet