Cell-type specific differences in antiretroviral penetration and the effects of HIV-1 Tat and morphine among primary human brain endothelial cells, astrocytes, pericytes, and microglia

Faculty Pharmacy Year: 2019
Type of Publication: ZU Hosted Pages: 134475
Authors:
Omnia Ahmed Emam Ismaiel
Journal: Neuroscience Letters Elsevier Volume:
Keywords : Cell-type specific differences , antiretroviral penetration , , effects    
Abstract:
To investigate, intracellular antiretroviral concentrations were measured in primary human astrocytes, microglia, pericytes, and brain microvascular endothelial cells (BMECs), and in an immortalized brain endothelial cell line (hCMEC/D3). HIV-1 Tat and morphine effects on intracellular antiretroviral concentrations also were evaluated
    
     
 
       

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