Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction

Faculty Science Year: 2020
Type of Publication: ZU Hosted Pages:
Authors:
Gihad Abousaty Mohamed Ismaeil Mekky
Journal: Scientific Reports Nature Volume:
Keywords : Multicellular , Neurovascular Unit Model , Assessing Hypoxia    
Abstract:
This 3D organoid model recapitulates characteristics of BBB dysfunction under hypoxic physiological conditions and when exposed to exogenous neuroinflammatory mediators and hence may have potential in disease modeling and therapeutic development.
    
     
 
       

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