Stromal cell-derived factor-1α predominantly mediates the ameliorative effect of linagliptin against cisplatin-induced testicular injury in adult male rats

Faculty Pharmacy Year: 2020
Type of Publication: ZU Hosted Pages:
Authors:
Rania Ali Mohamed Ali Elrashedy
Journal: cytokine Elsevier Ltd Volume: 136
Keywords : Stromal cell-derived factor-1α predominantly mediates , ameliorative    
Abstract:
This study provided mechanistic insights into the ameliorative effect of LG on cisplatin-induced testicular injury, through activation of SDF-1α/CXCR4 signaling pathway. Our findings suggest that LG can be a promising therapeutic candidate for cisplatin-induced testicular injury.
    
     
 
       

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