Cilostazol preconditioning alleviates cyclophosphamide-induced cardiotoxicity in male rats: Mechanistic insights into SIRT1 signaling pathway

Faculty Pharmacy Year: 2020
Type of Publication: ZU Hosted Pages:
Authors:
Journal: life Sciences Elsevier Volume:
Keywords : Cilostazol preconditioning alleviates cyclophosphamide-induced cardiotoxicity , male    
Abstract:
The study provided insights into the mechanism underlying the cardioprotective effect of cilostazol in CYP-treated rats through upregulation of SIRT1 signaling, suggesting that cilostazol might be a candidate modality for CYP-induced cardiotoxicity
   
     
 
       

Author Related Publications

  • Rania Ali Mohamed Ali Elrashedy, "Pioglitazone attenuates cardiac fibrosis and hypertrophy in a rat model of diabetic nephropathy", SAGE, 2012 More
  • Rania Ali Mohamed Ali Elrashedy, "Beneficial effects of pioglitazone against cardiovascular injury are enhanced by combination with aliskiren in a rat model of diabetic nephropathy", Willy, 2012 More
  • Rania Ali Mohamed Ali Elrashedy, "Bladder function in mice with inducible smooth muscle-specific deletion of the manganese superoxide dismutase gene", APS, 2015 More
  • Rania Ali Mohamed Ali Elrashedy, "Functional and morphological alterations of the urinary bladder in type 2 diabetic FVBdb/db mice", Elsevier Inc, 2016 More
  • Rania Ali Mohamed Ali Elrashedy, "Potential therapeutic roles of 10-dehydrogingerdione and/or pentoxifylline against calcium deposition in aortic tissues of high dietary cholesterol-fed rabbits.", Springer, 2018 More

Department Related Publications

  • Hebatallah Husseini Mohamed Atteia, "Protective Role of Epigallocatechin Gallate in a Rat Model of Cisplatin-Induced Cerebral Inflammation and Oxidative Damage: Impact of Modulating NF-κB and Nrf2", Springer, 2019 More
  • Rania Ali Mohamed Ali Elrashedy, "Essential oil and polyphenolics from Thymus satureioides Coss. counteract acrylamide-induced liver toxicity through suppression of NLRP3 inflammasome/NF-κB axis", Elsevier, 2023 More
  • Hebatallah Husseini Mohamed Atteia, "Pattern of fatty acids as modulator for dietary iron overload and its influences on testicular function of experimental rats", Academic Journals, 2013 More
  • Mohamed Mahmoud Swedy, "Chronic effects of clozapine administration on insulin resistance in rats: evidence for adverse metabolic effects.", elsevier, 2014 More
  • Mohamed Mahmoud Swedy, "Diabetic Renal Injury Induced in Experimental Rats-Role of Curcuminoids as Probable Therapeutic Agent", academic journals, 2013 More
Tweet