Potent Quinoline-Containing Combretastatin A-4 Analogues: Design, Synthesis, Antiproliferative, and Anti-Tubulin Activity

Faculty Pharmacy Year: 2020
Type of Publication: ZU Hosted Pages: 393
Authors:
Journal: Pharmaceuticals mdpi Volume: Pharmaceuticals 2020, 13, 393
Keywords : Potent Quinoline-Containing Combretastatin A-4 Analogues: Design, Synthesis,    
Abstract:
A novel series of quinoline derivatives of combretastatin A-4 incorporating rigid hydrazone and a cyclic oxadiazole linkers were synthesized and have demonstrated potent tubulin polymerization inhibitory properties. Many of these novel deri
   
     
 
       

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  • Zakareyah Kamel Abdelsamie, "Regioselective hydroxysulphenylation of derivatives of allylic alcohols and amines.", Tetrahedron Letters, 1986 More
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  • Zakareyah Kamel Abdelsamie, "Trifluoroacetoxysulphenylation of unsaturated nitriles as a route to lactones", Tetrahedron Letters, 1986 More
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