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Ameliorative role of Moringa oleifera plant extract against zinc oxide nanoparticles induced sperm and sex hormones abnormalities in male albino rats
Faculty
Science
Year:
2016
Type of Publication:
ZU Hosted
Pages:
Authors:
Sabha Elsayed Metwally Ali
Staff Zu Site
Abstract In Staff Site
Journal:
5th International Conference on Food,Agricultural and Biological Sciences (ICFABS-2016) Bangkok (Thailand) 5th International Conference on Food, Agricultural and Biological Sciences (ICFABS-2016) Bangkok (Thailand). Organised by URUAE.ORG
Volume:
Keywords :
Ameliorative role , Moringa oleifera plant extract
Abstract:
A nanoparticle is a nano-object with all three external dimensions in the size range of approximately 1–100 nm. Because of their small size, it can penetrate into the cell membrane and interfere in important cell functions. Zinc oxide nanoparticles (ZnO Nps) is one of the most commonly used types of nanoparticles that is widely used in different industries such as food additives, biosensors, resin production and electronic equipment, etc. Moringa oleifera (M.O.) extract has been shown to have strong antioxidant activity and decreases oxidative stress. The present investigation aimed to evaluate the toxic effects of ZnO Nps on sperm morphology and sex hormones (testosterone &FSH) and/or the ameliorative role of M.O. plant extract in vivo using male albino rats. The animals were divided into four main groups:Group1(control), group2 received M.O. extract (150mg/kg b.wt), group3 received suspension of ZnO Nps ( 7.5mg/kg b.wt) and group4 given ZnO Nps then were given M.O extract. The present results revealed that, the abnormalities in the sperm morphology and testosterone level induced by ZnO Nps were alleviated by the administration of M.O. plant extract (but no significant change in FSH level was observed).
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Department Related Publications
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Susan Attia Moawad, "Thymol-enriched diet alleviates the toxic impacts of zinc oxide nanoparticles on growth performance, blood biochemistry, oxidant/ antioxidant status and stress-related genes and histology of liver and gills in Oreochromis niloticus", ُُElsevier, 2023
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