First Report of aacC5-aadA74 Gene Cassette Array and Phage Tail Tape Measure Protein on Class 1 Integrons of Campylobacter Species Isolated from Animal and Human Sources in Egypt

Faculty Veterinary Medicine Year: 2020
Type of Publication: ZU Hosted Pages:
Authors:
Ahmed Mohamed Ahmed Amar
Journal: Animals MDPI Volume:
Keywords : First Report , aacC5-aadA74 Gene Cassette Array and    
Abstract:
Simple Summary: Campylobacter species are among the major causes of bacterial foodborne infections. Here, we investigate, for the first time, class 1 integrons and associated gene cassettes among pan drug-resistant (PDR), extensively drug-resistant (XDR), and multidrug-resistant (MDR) Campylobacter species isolated from livestock animals and humans in Egypt. Our results revealed alarming PDR (2.55%) and inordinate XDR (68.94%) and MDR (28.5%) Campylobacter isolates. None of the examined isolates were pan-susceptible. The existence of a novel gene cassette array, namely aacC5-aadA74 and a putative phage tail tape measure protein on class 1 integrons of Campylobacter species is the most highlighted novelty of the current study. Evidence from this study showed the possibility of Campylobacter–bacteriophage interactions as well as treatment failure in animals and humans due to horizontal gene transfer mediated by class 1 integrons.
    
     
 
       

Author Related Publications

  • Ahmed Mohamed Ahmed Amar , "Molecular Detection of Fluoroquinolone Resistance among Multidrug-, Extensively Drug-, and Pan-Drug-Resistant Campylobacter Species in Egypt", MDPI, 2022 More
  • Ahmed Mohamed Ahmed Amar , "Prevalence, antimicrobial susceptibility, virulence and genotyping of Campylobacter jejuni with a special reference to the anti-virulence potential of eugenol and beta-resorcylic acid on some multi-drug resistant isolates in Egypt", MDPI, 2022 More
  • Ahmed Mohamed Ahmed Amar , "Propidium Monoazide Quantitative Real-Time Polymerase Chain Reaction for Enumeration of Some Viable but Nonculturable Foodborne Bacteria in Meat and Meat Products", Mary Ann Liebert, Inc., 2018 More
  • Ahmed Mohamed Ahmed Amar , "Some studies on Klebsiella species affecting diseased sheep and goats", لايوجد, 1900 More
  • Ahmed Mohamed Ahmed Amar , "Advanced studies on Mycoplasma microorganisms in ducks.", لايوجد, 1900 More

Department Related Publications

  • Marwa Ibrahim Ibrahiem Abdelhamied, "Impact of Nigella sativa and Clove Oils on Cell Wall Genes Expression in Multidrug Resistant Staphylococcus aureus", Zagazig, Egypt, 2016 More
  • Sarah Youssef Abdelgelil Ahmed, "Use of biological nano zinc as a feed additive in quail nutrition: biosynthesis, antimicrobial activity and its effect on growth, feed utilisation, blood metabolites and intestinal microbiota", taylor and francis, 2021 More
  • Sarah Youssef Abdelgelil Ahmed, "Tomato pomace as a non-traditional feedstuff: Productive and reproductive performance, digestive enzymes, blood metabolites and the deposition of carotenoids into egg yolk in quail breeders", Elsevier Inc, 2022 More
Tweet