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Frontiers in Veterinary Science
Frontiers in Veterinary Science
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Abstract: |
Coronaviruses are the causative agents of many infectious diseases in human and
animals. These included severe acute respiratory syndrome (SARS), avian infectious
bronchitis (IBV) in poultry, Middle East respiratory syndrome (MERS), and coronavirus
disease 2019 (COVID-19) in humans. These results had considerable death burdens and
negative influences on social–economic life. Since the appearance of the outbreak of the
COVID-19 pandemic, continuous investigations have been carried out by researchers
to find active compounds, mainly from plants, as natural sources, that could inhibit
or stop the proliferation of the causative agent of COVID-19 (SARS-CoV-2). The most
common symptoms caused by infections with COVID-19 can include cough, fever,
and sore throat. Nevertheless, there is a shortage of active antiviral compounds for
treating different strains of coronavirus. Herbal medicine is a class of medication
that originates from nature and is aimed at decreasing the use of preservatives,
excipients, or other additives and, consequently, lesser side effects. The rapid spread
of COVID-19 infection besides the lack of knowledge about any treatments and the
growing concern of the public from the virus directed us toward writing this review article
in an aim to provide alternatives to the allopathic medicine use. There is a wealth of
chemical diversity in the naturally existing compounds, including their antiviral activities,
which may encourage their utilization as therapeutics against viral infections, including
coronaviruses. Themajority of publications on the herbal remedies of coronavirus,MERS,
or SARS focused primarily on the use of polar compounds. These substances displayed
encouraging inhibitory influences on coronavirus in humans. These include psoralidin,
scutellarein, silvestrol, tryptanthrin, caffeic acid, quercetin, myricetin, saikosaponin B2,
griffithsin (lectins), and isobavachalcone. Some other agents like lycorine may be useful,
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