Total synthesis of cyclic heptapeptide Rolloamide B

Faculty Pharmacy Year: 2013
Type of Publication: Article Pages: 2631-2633
Authors:
El-Feky, Said A, Katritzky, Alan R, Elagawany, Mohamed, El Khatib, Mirna, Caliskan, Eray, Davis, Emily Faith, Faidallah, Hassan M
DOI: 10.1039/c3cc39291k
Journal: CHEMICAL COMMUNICATIONS ROYAL SOC CHEMISTRY Volume: 49
Research Area: Chemistry ISSN ISI:000315648400010
Keywords : Total synthesis , cyclic heptapeptide Rolloamide ,    
Abstract:
The first total synthesis of Rolloamide B, a cyclic proline-enriched heptapeptide, is reported. This work features solution phase benzotriazole-mediated peptide synthesis ligating native amino acids.
    
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