Creating opening in existing beam is required to achieve the necessary layout of pipes and ducts, the transverse openings through beams are a source of potential weakness. This paper describes the result of an experimental investigation on the response of creating opening in reinforced concrete beams and the performance of strengthening in shear using either externally epoxy-bonded steel strips plate or FRP strips. The beams were instrumented and tested under three-point bending condition (3PB). The experimental program consisted of testing eight simply supported reinforced rectangular beams. The main parameters of study are the shape and the material used for strengthening. The deflection, failure load, failure mode and ductility of the retrofitted beams are discussed. A nonlinear finite element method NFEM analyses (Ansys program) was used to corroborate the results from the experimental study. The discontinuous web strengthening is failed to prevent the diagonal shear cracks at the bottom and top of the opening. The continuous web reinforcement retrofit succeeded to prevent the diagonal and horizontal cracks due to the existence of opening. The analytical results are compared with the data obtained from beam tests through the linear and nonlinear ranges up to failure. It was found that the FE models can identify the structural behavior of the tested beams and can be an excellent alternative of destructive laboratory test with an acceptable variation of results.