Pulmonary hypertension in COPD patients at Chest Departments of Zagazig University and Kobry EL Kobba Military Hospitals in 2014

Faculty Medicine Year: 2018
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Current Medicine Research and Practice Elsevier Volume:
Keywords : Pulmonary hypertension , COPD patients , Chest Departments    
Abstract:
Background: Pulmonary hypertension is the major cardiac complication of chronic obstructive pulmonary diseases (COPD). Also it is considered as a predictor of mortality independent of the pulmonary obstruction severity. Due to different methods of diagnosis and lack of the gold standard Right heart catheterization (RHC), diagnosis of PH in COPD patients could be missed and hence its treatment may be deficient which could impair the quality of life and lead to poor prognosis. So the aim of this work is to detect the frequency of pulmonary hypertension (PH) among stable COPD patients, and to evaluate the possible correlation of PH with the severity of the disease. Patients and methods: This study included 84 stable (COPD) patients with different grades of severity. All patients were subjected to Spirometric Pulmonary function test (PFTs), Electrocardiography (ECG) and Echocardiogram (ECHO). RHC was performed to mild and moderate COPD patients with severe PH diagnosed by Echocardiography. Results: PH was found among 33(39.3%) COPD patients; 17 (51.5%), 4 (12.1%) and 12(36.4%) were having mild, moderate and severe PH respectively as diagnosed by ECHO. Out of proportion PH was present in 3 cases only with mild COPD, and 4 cases with moderate COPD. A positive correlation was observed between echocardiography and RHC regarding measurement of mPAP (mmHg) with statistically significant difference (p < .05). Conclusion: 1-Pulmonary hypertension is a common sequel in COPD patients mostly with moderate severity, and is mainly of mild degree of PH. 2-Small proportion of COPD patients could develop PH disproportionate to the degree of airway obstruction which termed as out of proportion PH. 3-ECHO and even RHC are of crucial importance in detection of PH in patients with COPD in order not to miss cases with out of proportion PH.
   
     
 
       

Author Related Publications

  • Doaa Mostafa Mohamed Abdelhamied, "Sero-prevalence of anti-SARS-CoV-2 antibodies among healthcare workers: A multicenter study from Egypt.", elsevier, 2021 More
  • Doaa Mostafa Mohamed Abdelhamied, "Impact of glutathione-S-transferase gene polymorphisms on enzyme activity, lung function and bronchial asthma susceptibility in Egyptian children", Elsevier, 2012 More
  • Doaa Mostafa Mohamed Abdelhamied, "Role of adiponectin and other inflammatory biomarkers in COPD patients", Elsevier, 2013 More
  • Doaa Mostafa Mohamed Abdelhamied, "Value of the DECAF Score in Predicting Hospital Mortality in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease Admitted to Zagazig University Hospitals, Egypt", Elsevier, 2015 More
  • Doaa Mostafa Mohamed Abdelhamied, "Non-invasive Positive Pressure Ventilation and Exercise training in Patients with Stable Hypercapnic Chronic Obstructive Pulmonary Disease.", Elsevier, 2015 More

Department Related Publications

  • Mohammed Shabrawy Mahmoudi, "Arterial stiffness can occur early in mild-tomoderate chronic obstructive pulmonary disease", The Egyptian Journal of Bronchology, 2020 More
  • Walid Mansour Mohammed Amer, "Airway pressure release ventilation in comparison to synchronized intermittent mandatory ventilation in acute respiratory failure: a randomized controlled trial", Wolters Kluwer - Medknow, 2020 More
  • Walid Mansour Mohammed Amer, "Computed Tomography Imaging Assessment of the Effect of Vancomycin Paste on Poststernotomy Healing", Dove Press Ltd, 2021 More
  • Mohammed Walaa Saeed Meghawri, "Sonographic evaluation of different sclerosing agents in pleurodesis of malignant pleural effusion at Zagazig University Hospitals التقييم باستخدام الموجات فوق الصوتية للعوامل المصلبة المختلفة للانصباب الجنبي الخبيث في مستشفيات جامعة الزقازيق", The Egyptian Journal of Chest Diseases and Tuberculosis, 2018 More
  • Mohammed Walaa Saeed Meghawri, "Role of diaphragmatic rapid shallow breathing index in predicting weaning outcome in patients with acute exacerbation of COPD دور مؤشر التنفس الضحل السريع للحجاب الحاجز في توقع نتائج الفطام في مرضي التفاقم الحاد لمرضي السدة الرئوية المزمنة", International Journal of COPD, 2018 More
Tweet