The Potential Impact of Magnesium Supplementation on Cisplatin-Induced Nephrotoxicity in Adult Male Albino Rats

Faculty Medicine Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Wafa Ibrahim Suleiman
Journal: Ain Shams Journal of Forensic Medicine and Clinical Toxicology جامعة عين شمس Volume:
Keywords : , Potential Impact , Magnesium Supplementation on Cisplatin-Induced Nephrotoxicity    
Abstract:
Cisplatin has been considered one of the most effective chemotherapeutic agents. It is associated with numerous toxicities at therapeutic doses like ototoxicity, gastrotoxicity, myelosuppression, allergic reactions and nephrotoxicity. The synergistic effects of Cisplatin and magnesium deficiency are believed to contribute to renal dysfunction.cisplatin induced andomized in the kidney function andMg supplementation ameliorates it. It is recommendedto do further investigations to determine therole of magnesium in cisplatin induced nephrotoxicity.
    
     
 
       

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