PROTECTIVE EFFECTS OF TOMATO LYCOPENE AND ZINGIBER OFFICINALE EXTRACTS ON GENTAMICIN-INDUCED NEPHROTOXICITY IN ADULT ALBINO RATS (COMPARATIVE STUDY)

Faculty Medicine Year: 2018
Type of Publication: ZU Hosted Pages:
Authors:
Journal: مجلة الزقازيق للطب الشرعي والسموم جامعة الزقازيق Volume:
Keywords : PROTECTIVE EFFECTS , TOMATO LYCOPENE , ZINGIBER OFFICINALE    
Abstract:
Gentamicin (GEN) is an aminoglycoside antibiotic that is widely used in clinical practice in treatment of severe gram negative bacterial infections. Tomato lycopene (LYC) and Zingiber officinaleethyl acetate extract (ZOEAE) are powerful antioxidants against free radicals and oxidative attacks.Supplementation with antioxidants e.g. LYC and ZOEAE in GEN treated patients had beneficial impacts through alleviating the oxidative stress and improving renal functions.
   
     
 
       

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