Simple HPLC method for the analysis of some pharmaceuticals

A simple, selective, and accurate high performance liquid chromatographic method for the determination of cephalexine, cefotaxime, and salbutamol sulphate was developed. The suggested method uses ODS column with methanol-phosphate buffer (pH 7) 6:4 as a mobile phase. The mean percentage recovery ranged from 97.4 to 98.8. The proposed method was applied to the determination of the selected drug in some pharmaceutical preparations. The statistical analysis of the results obtained was compared favourably with those given with the official method.