Bacterial wilt disease of Solanaceae plants caused by Ralstonia solanacearum is an economic quarantine disease worldwide. The disease is difficult to control when established himself in cultivated area. This study was concerned to evaluate seven different organic amendments to control the disease on potato and tomato plants, under artificial inoculation conditions. Obtained results revealed that all of animal manure, poultry and dove compost were increased population of fungi, bacteria and actinomycetes in root rhizosphere, but did not affect the population of Ralstonia solanacearum cell concentration. However, animal manure, mixture1 (animal manure + vegetarian) and mixture 2 (animal manure + poultry) compost decreased population of pathogen cell concentration in root rhizosphere. The least percentage of disease incidence and severity were obtained when animal manure, mixture1 and mixture 2 composts were used at 10-20% concentrations in soil infested with bacterial wilt pathogen, followed by vegetarian (sugar cane) and vegetarian (etr). While, poultry and dove composts were lower effective in decreasing percentage of disease incidence and severity under artificial inoculation conditions. The animal manure, mixture 1, mixture 2, vegetarian (sugar cane), vegetarian (etr) composts increased tubers number and weight, number of tomato shoots and dry weight of leaves, stems and roots of potato and tomato plants as well as chlorophyll a and b but decreased carotenoids in plant leaves. While, Poultry and dove composts were less effective on these parameters. Both of polyphenol oxidase and peroxidase activity were increased at different degrees in plants treated with different composts.