Pyrrolizidine alkaloids in members of the Boraginaceae from Sinai (Egypt)

Faculty	Pharmacy	Year:	1998
Type of Publication:	Article	Pages:	619-636
Authors:	Witte, L, Wink, M, El-Shazly, A, El-Domiaty, M	DOI:	10.1016/S0305-1978(98)00028-3
Journal:	BIOCHEMICAL SYSTEMATICS AND ECOLOGY PERGAMON-ELSEVIER SCIENCE LTD	Volume:	26
Research Area:	Biochemistry \& Molecular Biology; Environmental Sciences \& Ecology; Evolutionary Biology	ISSN	ISI:000075497200003
Keywords :	Paracaryum rugulosum, Paracaryum intermedium, Anchusa milleri, Gastrocotyle hispida, Anchusa arvensis, Lappula spinocarpos, Alkanna orientalis, Alkanna tubeinculata, Trichodesma africanum, Boraginaceae, pyrrolizidine alkaloids, gas liquid chromatography (GLC), GLC mass spectrometry
Abstract:	Altogether 40 pyrrolizidine alkaloids were detected in the alkaloid extracts of Paracaryum rugulosum, P. intermedium, Anchusa milleri, Gastrocotyle hispida (syn. Anchusa hispida), Anchusa arvensis, Lappula spinocarpos, Trichodesma africanum, Alkanna orientalis, and Alkanna tuberculata (syn, A, tinctoria) which were analyzed by capillary GLC and GLC-MS. 24 alkaloids were unambiguously identified by comparing their specific retention indices and mass fragmentations with those of authentic alkaloids and literature data. The relevance of PAs as chemical defence compounds for desert plants against herbivores is discussed. (C) 1998 Elsevier Science Ltd. All rights reserved.
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