Journal: |
The Egyptian Journal of Internal Medicine
Wolters Kluwer - Medknow
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Abstract: |
Introduction
The increased prevalence of diabetes has led to an increase in its vascular
complications such as coronary heart disease, stroke, diabetic nephropathy
(DN), and end-stage renal disease. The growing epidemic of type 2 diabetes
led to increased incidence of DN. DN is characterized by proteinuria.
Objective
The aim of the study was to estimate the prevalence of diabetic kidney disease in
patients with type 2 diabetes mellitus.
Patients an methods
This study included 151 patients with type 2 diabetes mellitus. After fulfilling the
inclusion and exclusion criteria, all patients were submitted to these investigations:
complete blood count, fasting blood glucose, and glycosylated hemoglobin, blood
urea, serum creatinine, serum uric acid, calculation of estimated glomerular
filtration rate using modification of diet in renal disease equation, lipid profile,
serum albumin, urine analysis, and urinary albumin creatinine ratio.
Results
Of the patients, 60.3% have normoalbuminuria, 31.8% have microalbuminuria, and
7.9% have macroalbuminuria. Regarding glomerular filtration rate grades, 25.8% of
the patients are of G1, 31.8% G2, 16.6% G3a, 16.6% G3b, 6.6% G4, and 2.6% are
of G5. There is a significant increase in grading in patients with macroalbuminuria;
also, most normoalbuminuric patients are G1 and G2. Of the studied patients,
53.6% are at low risk of chronic kidney disease progression, 9.9% are at moderate
risk, and 36.4% are at high risk.
Conclusion
The prevalence of DN is increasing, partly due to the growing epidemic of type 2
diabetes so we have to detect it as early as possible to apply the proper measures to
prevent or delay its progression.
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