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Serum vitamin D levels in acute stroke patients
Faculty
Medicine
Year:
2019
Type of Publication:
ZU Hosted
Pages:
Authors:
Fayrouz Othman Salim Othman
Staff Zu Site
Abstract In Staff Site
Journal:
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery springer
Volume:
Keywords :
Serum vitamin , levels , acute stroke patients
Abstract:
Background: Vitamin D deficiency has been proposed as a risk factors of cerebrovascular stroke. Objectives: The aim of this study was firstly, to assess the serum level of vitamin D in cerebral stroke patients and secondly, to examine if its deficiency was associated with stroke severity and outcome. Methods: We utilized a case-control study design and recruited 138 acute stroke patients and 138 age- and sex matched controls from subjects attending outpatient clinic for other reasons. All participants were subjected to full general and neurological examination. Brain imaging CT and/or MRI was performed. Blood samples were collected for measurement of serum level of vitamin D (ng/ml) by ELISA, alkaline phosphatase, serum calcium, and phosphorous. The stroke severity was assessed by the National Institutes of Health Stroke Scale (NIHSS) and stroke outcome was assessed by modified Rankin Scale (mRS). Results: Stroke patients had significant lower levels of vitamin D compared with the control group. Vitamin D deficiency remained significantly associated with the NIHSS stroke severity score and the mRS 3-month stroke outcome after controlling for other significant factors such as age, dyslipidemia, and infarction size using multivariable logistic regression analysis. Conclusion: Our results demonstrated that stroke patients suffer from vitamin D deficiency, which was associated with both stroke severity and poor outcome. Vitamin D supplementation could exert a therapeutic role in the management of cerebral stroke. Keywords: Vitamin D, Stroke, NIHSS, mRS
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Department Related Publications
Ahmed Adel Hassan Muhamad, "التعدد الشكلى لجينات الصنف الثانى من مولدات المضادات المحمولة على كرات الدم البيضاء البشرية فى حالات اصابات الكلى المزروعة بارتجاع الالتهاب الكبدى الناتج عن الاجسام المضادة "أ"", لايوجد, 1900
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Usama Mohamed Ahmed Hassanein, "علاقة النحاس والسيريولوبلازمين بالمراحل المختلفة للاعتلال الكلوي السكري في مرض السكر من النوع الثاني", لايوجد, 1900
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Usama Mohamed Ahmed Hassanein, "دراسة الارتباط بين درجة احساس القرنية ودرجة تاثير الاعصاب الطرفية والشرايين في مرض السكر ", لايوجد, 1900
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Ehab Barsom Fahim Meawad, "البروتين المرتبط بالرتيينول فى البول كوسيلة لاكتشاف المبكر للاعتلال الكلوى السكرى ( تم اجراء الدراسة بمستشفيات جامعة الزقازيق)", لايوجد, 1900
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