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Phytochemical and pharmacological studies of Dalbergia sissoo growing in Egypt
Faculty
Pharmacy
Year:
1999
Type of Publication:
Article
Pages:
54-62
Authors:
SARG, T, Ateya, AM, Abdel-Ghani, A, Badr, W, Shams, G
DOI:
10.1076/phbi.37.1.54.6310
Journal:
PHARMACEUTICAL BIOLOGY SWETS ZEITLINGER PUBLISHERS
Volume:
37
Research Area:
Plant Sciences; Medical Laboratory Technology; Pharmacology \& Pharmacy
ISSN
ISI:000081610600012
Keywords :
Dalbergia sissoo Roxb., isoflavones, sterols and triterpenes, fatty acids, smooth muscle relaxant, anti-inflammatory, antipyretic, analgesic, estrogen-like activity
Abstract:
The isoflavones irisolidone, biochanin-A, muningin, tectorigenin, prunetin, genestein, sissotrin and prunetin-4-O-galactoside, the flavone nor-artocarpotin, and beta-amyrin, beta-sitosterol and stigmasterol were isolated and identified from the green branches of aerial parts of Dalbergia sissoo Roxb. using silica gel column chromatography and spectral analysis. Also, 13 fatty acids were identified. The alcohol extract of the green branches of aerial parts showed a dose-dependent inhibitory effect an the motility of isolated rabbit duodenum, pronounced bronchodilation, as well as significant anti-inflammatory, antipyretic, analgesic, and estrogen-like activities. The plant extract was well-tolerated by rats.
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