Tuning the mechanical, microstructural, and cell adhesion properties of electrospun e-polycaprolactone microfibers by doping selenium-containing carbonated hydroxyapatite as a reinforcing agent with magnesium ions

Faculty Science Year: 2019
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Journal of Materials Science Springer Volume:
Keywords : Tuning , mechanical, microstructural, , cell adhesion properties , electrospun    
Abstract:
The flexible lattice of hydroxyapatite (HAP) allows for doping with ions widely varying in size and charge and these ions can impart a range of properties that could be harnessed for high technology applications. However, incorporation of combinations of ions, each of which endows HAP with different properties, has rarely been explored, let alone in combination with polymers. Carbonated hydroxyapatite (CHAP) dually doped with magnesium and selenite ions (Mg– Se–CHAP) was synthesized at different contents of the Mg 2? dopant and inte- grated within electrospun e-polycaprolactone (PCL) microfibers. The formula Mg x Ca ðÞ PO 10xðÞ 4 5:8 ðÞ SeO 2 0:2 OHðÞ represented the ceramic component of Mg– Se–CHAP/PCL fibers, whose properties were studied for different values of the 2 stoichiometric parameter x in the 0.0 B x B 0.5 range. The structural investigation indicated that the lattice parameter a decreased with the addition of Mg from x =0tox = 0.3, at which point it reached its minimal value of 9.414 A ˚ , while the lattice parameter c increased with the addition of Mg 2? from x =0to x = 0.3, at which point it reached its maximal value of 7.050 A logical properties depended strongly on the Mg 2? ˚ . The morpho- content, as the fibrous scaffolds became more networked, rougher on the surface, and less porous with the addition of Mg 2? . All of these surface properties affected the human fibroblastic HFB4 cell response to these materials. While the cell viability tests indicated a 2?
   
     
 
       

Author Related Publications

  • Salwa Fahim Ibrahim Mansour, "Facile modification of polycaprolactone nanofibers with hydroxyapatite doped with thallium ions for wound and mucosal healing applications", ELSEVIER, 2021 More
  • Salwa Fahim Ibrahim Mansour, "Morphological behaviors of brushite/vivianite nanocomposites and their potency for Se(IV) and Cd(II) removal from aqueous solutions", ELSEVIER, 2020 More
  • Salwa Fahim Ibrahim Mansour, "Nanoarchitectonics of Hydroxyapatite/Molybdenum Trioxide/ Graphene Oxide Composite for Efficient Antibacterial Activity", Springer, 2021 More
  • Salwa Fahim Ibrahim Mansour, "Nanofibers scaffolds of co-doped Bi/Srhydroxyapatite encapsulated into polycaprolactone for biomedical applications", ELSEVIER, 2021 More
  • Salwa Fahim Ibrahim Mansour, "Structural, ferroelectric, magnetic and magnetoelectric properties of (1-x) Ba0.85Ca0.15Zr0.1Ti0.9O3 -x La0.67Sr0.33MnO3 lead-free magnetoelectric composites", ELSEVIER, 2020 More

Department Related Publications

  • Nabil Mohamed Mohamed Hasana, "Elemental Analysis of Egyption Phosphate Fertilizer Components Samples by TGA, DTA and IR Methods", www.iosrjournals.org, 2013 More
  • Abdulrahman Abdullah Awadallah, "Novel SiC nanoparticles-containing Sn–1.0Ag–0.5Cu solder with good drop impact performance", Elsevier, 2013 More
  • Hesham Mohamed Zaki Mostafa, "Magnesium-Zinc Ferrite Nanoparticles: Effect of Copper Doping on the Structural, Electrical and Magnetic Properties,", American Scientific Publishers, 2013 More
  • Abdullah Fathi Aly Saad, "The track nanotechnology", Radiation Measurements (Elsevier Science), Vol. 44, (2009) 1109- 1113.., 2009 More
  • Salwa Fahim Ibrahim Mansour, "Composition dependence of discontinuous magnetization in Li- Ti ferrites", J.Phys. D Appl., 1993 More
Tweet