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Prognostic Value of Percentage of Positive to Total Excised Axillary Lymph Nodes in Egypt with Triple Negative Breast Cancer: Multiple-Centers Experience
Faculty
Medicine
Year:
2018
Type of Publication:
ZU Hosted
Pages:
719-732
Authors:
Mansour Mohamed Morsy umar
Staff Zu Site
Abstract In Staff Site
Journal:
International Journal of Life Sciences International Journal of Life Sciences
Volume:
6
Keywords :
Prognostic Value , Percentage , Positive , Total Excised
Abstract:
Background: The total number of axillary lymph nodes [LNs] is the most important prognostic factor in breast cancer. Over long times, different studies indicated that the lymph node ratio [LNR] might predict outcome better than the number of positive LNs. The aim of this retrospective study was to evaluate prognostic value of the lymph node ratio [LNR] in triple negative breast cancer [TNBC]. Materials and Methods: sixety patients with triple negative breast cancer [TNBC] at Zagazig University Hospitals and Fakous Cancer Center were included. We analyzed the impact lymph node ratio [LNR] on the disease free survival [DFS] and overall survival [OS] [calculated by Kaplan–Meier method]. Results: our results showed that the optimal cut off value of LNR value was 0.65, and the optimal cut off value of PLN. The Kaplan–Meier survival analysis showed the higher value of Mean disease free survival among all patients was 33.21 months and 3 year DFS was 50.6%. Disease free survival was significantly longer in those with LNR ≤ 0.65 than those with LNR > 0.65 [Mean: 33.34 months versus 27.46 months; 3year DFS 56.4% versus 36.9% respectively]. Mean overall survival among all patients was 36.90 months and 3 year OS was 50.4%. Overall survival was significantly longer in those with LNR ≤ 0.65 than those with LNR > 0.65 [Mean: 39.40 months versus 29.63 months; 3 year OS 73.8% versus 23.3% respectively]. Conclusion: These results suggest that TNBC patients with lower value of LNR good prognosis than with high LNR patients. The LNR is an independent prognostic factor, thus, LNR may be added to the current staging system.
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Mansour Mohamed Morsy umar, "?Neck dissection in papillary thyroid carcinoma: when and why", The Egyptian Society of Surgeons (ESS), 2014
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Mansour Mohamed Morsy umar, "Challenges of Surgical Management of Left Colonic Emergencies: A Multicentre Study", cairo university, faculty of medicine, surgery departmentr, 2018
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Mansour Mohamed Morsy umar, "SIMULTANEOUS REPAIR OF BILATERAL INGUINAL HERNIA BY LICHTENSTEIN REPAIR VERSUS STOPPA OPERATION", Morse Florse, 2018
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Mansour Mohamed Morsy umar, "Divided Laparoscopic Cholecystectomy for Unusual Gall Stones Complication of Mirizzi’s Syndrome", The Korean Society of Endoscopic and Laparoscopic Surgeons, 2015
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Mansour Mohamed Morsy umar, "One Stage Forehead Flap for Nasal Reconstruction اصلاح الأنف عن طريق عمل سديلة من الجبهة فى مرحلة واحدة", Science Publishing Group, 2015
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Department Related Publications
Fady Mehaney Habib Salamh, "Mesh or not in the repair of complicated umbilical hernia in cirrhotic patients with decompensated liver cell failure", Wolters Kluwer - Medknow, 2018
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Mohamed Ibrahim Ahmed Mansour, "Outcomes of side-to-end versus end-to-end colorectal anastomosis in non-emergent sigmoid and rectal cancers: randomized controlled clinical trial", pISSN 2287-9714 eISSN 2287-9722 www.coloproctol.org, 2022
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Mohamed Ibrahim Ahmed Mansour, "Post-Cholecystectomy Gallbladder Remnant and Cystic Duct Stump Stone: Surgical Pitfalls, Causes of Occurrence and Completion Cholecystectomy (Open versus Laparoscopic) as a Safe Surgical Option of Treatment: Short and Long Term Outcome. Randomized Controlled Clinical Trial", Department of surgery, Zagazig University hospitals, 2021
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Mohamed Mahmoud Mokhtar, "laparoscopy versus laparotomy in evaluation of penetrating abdominal injuries.", internatinal journal of advanced research, 2018
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Mohamed Mahmoud Mokhtar, "Comparison Of Onlay Versus Sublay Mesh Repair For Management of Paraumbilical Hernia", Zagazig University Medical Journal, 2020
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