Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
HBV genotyping in chronic HBV patients in southwestern Saudi Arabia
Faculty
Medicine
Year:
2015
Type of Publication:
ZU Hosted
Pages:
Authors:
Ahmed Mohamed Mourad Asaad
Staff Zu Site
Abstract In Staff Site
Journal:
Journal of Family and Community Medicine ScienceDirect
Volume:
22
Keywords :
, genotyping , chronic , patients , southwestern Saudi Arabia
Abstract:
The distribution of hepatitis B virus genotypes in Saudi Arabia is largely unknown. To the best of our knowledge there are no data available about HBV genotypes in southwestern region of the country. This study aimed to determine the epidemiologic distribution of hepatitis B virus genotypes in chronic hepatitis B patients in southwestern region, and to verify possible correlations between these genotypes and the clinical symptoms. A total of 160 patients with chronic hepatitis B infection were enrolled in this study. Sera were tested for liver function tests, hepatitis B virus markers and DNA load by standard procedures. HBV genotyping was performed by 2-tube nested PCR for determination of six genotypes (A-F). Genotype D was the most common, found in 135 (84.4%) patients, followed by A (18; 11.3%) and E (7; 4.3%). The rate of HBeAg positivity in genotype D patients was significantly lower compared with that in genotype A and E patients (p=0.01). There was no significant association between HBV genotypes and age, gender, liver function tests, or HBV DNA load. Genotypes D and E were predominant in chronic hepatitis B patients in southwestern Saudi Arabia. Awareness of hepatitis B virus serologic and genotypic patterns might help in the formulation of management plans, predicting clinical outcomes and updating prevention strategies.
Author Related Publications
Ahmed Mohamed Mourad Asaad, "Automation in microbiology laboratories: Well begun is half done", LongDom Press, 2016
More
Ahmed Mohamed Mourad Asaad, "Antimicrobial activity of Silvadoriapersica (Miswak) against multi-drug resistant bacterial clinical isolates", Hindawi, 2016
More
Ahmed Mohamed Mourad Asaad, "Clinical significance of coagulase-negative Staphylococci isolates from nosocomial bloodstream infections", Taylor and Francis, 2016
More
Ahmed Mohamed Mourad Asaad, "Antimicrobial resistance: Hope for the best and prepare for the worst", imedpub, 2015
More
Ahmed Mohamed Mourad Asaad, "Viral etiology of respiratory infections in children in Najran, Saudi Arabia, using the multiplex RT-PCR", Saudi Medical Journal, 2014
More
Department Related Publications
Ashwak Mohamed Foad Abotaleb, "استخدام سلسله تفاعل البلمره المتسلسل مع زوج واحد من البادئات لتشخيص تفطر الدم المسبب بثلاثة انواع من الفطور في الاطفال حديثى الولادة", لايوجد, 1900
More
Ayman Abdelrahman Hussinn, "الخصائص السريرية و الميكروبية لعدوى المستشفيات التى تسببها انواع البكتيريا الراكدة", لايوجد, 1900
More
Hanan Mohamed Elsayed Ibrahiem, "Diagnosis of Acute Bacterial Endophthalmitis By Nested Polymerase Chain Reaction", لايوجد, 1900
More
Hanan Mohamed Elsayed Ibrahiem, "Chlamydia trachomatis detection by polymerase chain reaction (PCR) in infertile women using a tubal cytobruch during laparoscopy. 1 /11/1999 Zagazig University Medical J ", لايوجد, 1900
More
Alaaeldeen Abdelbaset Hadhoud, "Plasmid profile analysis of tmp resistance negative bacilli among patients unit", لايوجد, 1900
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف