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Serum vitamin D levels in acute stroke patients
Faculty
Medicine
Year:
2019
Type of Publication:
ZU Hosted
Pages:
Authors:
Ahmed Farouk Elsayed Elsayed Ahmmed
Staff Zu Site
Abstract In Staff Site
Journal:
Environmental Pollution Speinger
Volume:
Keywords :
Serum vitamin , levels , acute stroke patients
Abstract:
Background Vitamin D deficiency has been proposed as a risk factors of cerebrovascular stroke. Objectives The aim of this study was firstly, to assess the serum level of vitamin D in cerebral stroke patients and secondly, to examine if its deficiency was associated with stroke severity and outcome. Methods We utilized a case-control study design and recruited 138 acute stroke patients and 138 age- and sex-matched controls from subjects attending outpatient clinic for other reasons. All participants were subjected to full general and neurological examination. Brain imaging CT and/or MRI was performed. Blood samples were collected for measurement of serum level of vitamin D (ng/ml) by ELISA, alkaline phosphatase, serum calcium, and phosphorous. The stroke severity was assessed by the National Institutes of Health Stroke Scale (NIHSS) and stroke outcome was assessed by modified Rankin Scale (mRS). Results Stroke patients had significant lower levels of vitamin D compared with the control group. Vitamin D deficiency remained significantly associated with the NIHSS stroke severity score and the mRS 3-month stroke outcome after controlling for other significant factors such as age, dyslipidemia, and infarction size using multivariable logistic regression analysis. Conclusion Our results demonstrated that stroke patients suffer from vitamin D deficiency, which was associated with both stroke severity and poor outcome. Vitamin D supplementation could exert a therapeutic role in the management of cerebral stroke.
Author Related Publications
Ahmed Farouk Elsayed Elsayed Ahmmed, "Dietary Supplementation with Biobran/MGN-3 Increases Innate Resistance and Reduces the Incidence of Influenza-like Illnesses in Elderly Subjects: A Randomized, Double-Blind, Placebo-Controlled Pilot Clinical Trial", MDPI, 2021
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Ahmed Farouk Elsayed Elsayed Ahmmed, "Infarction Size, Interleukin-6, and Their Interaction Are Predictors of Short-Term Stroke Outcome in Young Egyptian Adults", Journal of Stroke and Cerebrovascular Diseases, 2016
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Ahmed Farouk Elsayed Elsayed Ahmmed, "Association of Plasma Epidermal Growth Factor with Cognitive Function in Parkinson Disease Patients", Egypt J Neurol Psychiat Neurosurg, 2016
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Ahmed Farouk Elsayed Elsayed Ahmmed, "Statins attenuate hyperalgesia and inflammation in experimentally induced acute and neuropathic pain in rats", Ain-Shams Journal of Anaesthesiology, 2016
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Ahmed Farouk Elsayed Elsayed Ahmmed, "The Effect of Probiotics on Interleukin- 8 and Intestinal Flora in Irritable Bowel Syndrome in Hospital of Zagazig University", Zagazig Nursing Journal, 2016
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Department Related Publications
Gamal Alsayed Breek Mohamed, "وظائف النهوية الرئوية والاعراض التنفسية لعمال الشاي ", لايوجد, 1900
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Samyah Saied Ali Elgohary, "مقارنة بين الأثر الوقائى لكل من الألفاتوكوفيرول و الزنك على تسمم الخصيتين بالكادميوم لذكور الجرذان البيضاء البالغة .", لايوجد, 1900
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