Assessment of supportive needs is the requirement to plan supportive care program for cancer patients. The aim of this study was to highlight the supportive care needs in relation to psychological distress level among women under treatment for breast cancer. Research design: A cross - sectional descriptive design was used; the study sample including 200 women, was recruited at the oncology clinics in Zagazig University Hospitals. Tools: Three tools were used for data collection: 1) Demographic data and medical history. 2) The Supportive Care Needs Survey- short form questionnaire, which covers five domains of needs (physical and daily living, health system and information, psychological, patient care and support and sexuality domains. 3) Distress thermometer scale. Results revealed that the highest affected domain was in physical and daily living domain followed by health system and information. On the other hand , the lowest domain was in sexual domain. patients had moderate to sever distress (74%) , younger participants had more unmet needs in all domains and high level of psychological distress. Married women had more unmet supportive care needs. Conclusion: A highly statistically significant positive correlation was found between psychological distress level and total needs. Further studies are needed for ongoing assessment of patients' needs and their psychological distress level to ensure monitoring and intervention to meet various needs of patients during treatment and to confirm this study results.