Lakes are one of the most important characteristics of Egypt’s coastal areas. However, deteriorating condition of these lakes due to industrialization, land reclamation, agricultural practices, overfishing, bird hunting, and coastal erosion is serious. Many challenges are faced by these lakes, some of which are the most polluted lakes in Egypt where they receive large quantities of agricultural, industrial, and municipal wastes through several drains and from factories around them. In addition, Egypt’s Mediterranean coast and the Nile Delta have been identified highly vulnerable to climate change impacts. Adaptive management is the best approach for addressing this type of complex problem. The main objective of this chapter is to classify Egypt’s lakes and depressions and to evaluate the land resources status of Egypt’s coastal lakes. Also, the challenges facing the sustainable development of these lakes were identified. Adaptive management approach would facilitate the investigation and classification of Egypt’s lakes and depressions. Egypt has been distinguished into four adaptive management zones based on different factors such as the climatic conditions in combination with the agriculture, physiography, natural resources, and other issues affecting the socioeconomic activities