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A comparative study of topical cantharidin and intralesional PPD to treat molluscum contagiosum
Faculty
Medicine
Year:
2019
Type of Publication:
ZU Hosted
Pages:
Authors:
Fatheah Mohammed Ahmed Abdullah khattab
Staff Zu Site
Abstract In Staff Site
Journal:
J Cosmet Dermatology. Taylor & Francis Group
Volume:
Keywords :
, comparative study , topical cantharidin and intralesional , , treat
Abstract:
Background: The immune system plays an important part in the clearance of molluscum contagiosum (MC) and, therefore, there has lately been a trend in using immunotherapy in MC therapy. Tuberculinpurified protein derivatives (PPDs) and topical cantharidin have not earlier been compared with their effectiveness in therapy Aim: The aim of this research was to determine the effectiveness and security of intralesional immunotherapy in the therapy of MC with tuberculin PPD versus topical cantharidin Patients and methods: Twenty patients with various MC lesions received topical cantharidin as control (group A) and 20 MC patients received intralesional tuberculin PPD following prior intradermal immunity tests (group B). Results: Complete clearance of lesions was detected in 90.0% of patients in the cantharidin group; the partial response was detected in10.0% of the patients. However, in the PPD group, 85% of the patients showed a complete response and 15% showed a partial response, with no significant difference in the clinical response between the two groups. Mild side effects were detected. Conclusion: The results suggest that intralesional PPD and topical cantharidin 0.7% are effective and safe treatment modalities, but benefits of intralesional PPD is being a simple, effective and safe treatment with tolerable pain and can be an alternative treatment for multiple resistant types
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Department Related Publications
Eman Salah El Din Moahmed Helmy Abdul El Baky, "Hydroxyurea-induced dermatomyositis: true amyopathic dermatomyositis or dermatomyositis-like eruption?", International Journal of Dermatology, 2012
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