Bis(tri-tert-butylphosphine)palladium(0)-catalyzed iodine–fluorine exchange at closo-carboranes.

Faculty Science Year: 2018
Type of Publication: ZU Hosted Pages:
Authors:
Ahmed Khalil Elsayed Khalil
Journal: Bioorganic & Medicinal Chemistry Wiley Volume:
Keywords : Bis(tri-tert-butylphosphine)palladium(0)-catalyzed iodine–fluorine exchange , closo-carboranes.    
Abstract:
The bis(tri-tert-butylphosphine)palladium(0) [Pd(tBu3P)2]-catalyzed synthesis of fluorinated closo-carboranes from 3D aromatic iodo-closo-carboranes by nucleophilic halogen exchange using silver(I) fluoride is described. Fluorination of 2-i
    
     
 
       

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  • Ahmed Khalil Elsayed Khalil, "Synthesis, biological evaluation, and radioiodination of halogenated closo-carboranylthymidine analogues", ACS, 2011 More
  • Ahmed Khalil Elsayed Khalil, "Iodine monochloride facilitated deglycosylation, anomerization, and isomerization of 3-substituted thymidine analogues.", Taylor & Francis, 2014 More
  • Ahmed Khalil Elsayed Khalil, "Synthesis and evaluation of thymidine kinase 1-targeting carboranyl pyrimidine nucleoside analogs for boron neutron capture therapy of cancer.", Elsevier, 2015 More
  • Ahmed Khalil Elsayed Khalil, ": Design, synthesis, and biological evaluation of aminothiazole derivatives against the fungal pathogens Histoplasma capsulatum and Cryptococcus neoformans.", Elsevier, 2014 More
  • Ahmed Khalil Elsayed Khalil, "2'-Chloro,2'-fluoro ribonucleotide prodrugs with potent pan-genotypic activity against Hepatitis C Virus replication in culture", ACS, 2017 More

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