Synthesis and evaluation of thymidine kinase 1-targeting carboranyl pyrimidine nucleoside analogs for boron neutron capture therapy of cancer.

Faculty Science Year: 2015
Type of Publication: ZU Hosted Pages:
Authors:
Ahmed Khalil Elsayed Khalil
Journal: Bioorganic & Medicinal Chemistry Elsevier Volume:
Keywords : Synthesis , evaluation , thymidine kinase 1-targeting carboranyl    
Abstract:
A library of sixteen 2nd generation amino- and amido-substituted carboranyl pyrimidine nucleoside analogs, designed as substrates and inhibitors of thymidine kinase 1 (TK1) for potential use in boron neutron capture therapy (BNCT) of cancer
    
     
 
       

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