Iodine monochloride facilitated deglycosylation, anomerization, and isomerization of 3-substituted thymidine analogues.

Faculty Science Year: 2014
Type of Publication: ZU Hosted Pages:
Authors:
Ahmed Khalil Elsayed Khalil
Journal: European Journal of Medicinal Chemistry Taylor & Francis Volume:
Keywords : Iodine monochloride facilitated deglycosylation, anomerization, , isomerization    
Abstract:
The reaction of thymidine, 3-mono-, and 3,3',5'-trialkylsubstitued thymidine analogues with iodine monochloride (ICl) was investigated. Treatment with ICl resulted in rapid deglycosylation, anomerization, and isomerization of thymidine and
   
     
 
       

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